Boss Pearl
The full library unlock.
- Every collection — organized by drug and by diagnosis
- Psychopharm deep dives & diagnostic tools
- 100 Interview Tips eBook — FREE (a $39.99 value)
- New member posts every week
The Pearls & Prep Podcast
Pearls & Prep
Psychiatric Case Studies
There are two kinds of clinicians — the ones who follow algorithms, and the ones who understand the “why.” Each episode walks a real-world psychiatric case from chart review to treatment plan: psychopharmacology, DSM-5-TR differentials, and the pearls that stick. Built for PMHNP students, new grads, and practicing clinicians.
Hosted by NP Z, Duke-trained Psychiatric Nurse Practitioner · New episodes every Tuesday
50Free Pearls study guide
127Episodes
8Spots max per sim group
Listen wherever you get podcasts
Most Popular Offers
Pick Your Pearl
A supplement to your formal PMHNP education — built to fill the gaps between the classroom and your first patient. Start free with the 50 Pearls guide, then go deeper with the tier that fits where you are.
Mafia Pearl
$100/month — live mock patients, real pressure.
- 2 live mock-patient simulations every month — NP Z plays the patient
- He challenges your diagnosis, medication selection & interview
- Groups capped at 8 — everyone gets reps
- Open office hours with NP Z
- Mentorship for students & new grads
Pearls Plus
The lightest way in.
- Member-only posts & extras
- Support the show you study with
- Upgrade to Boss Pearl anytime
Prefer one-and-done tools? BOARD BOMBS™ — 250 board-style questions ($49.99) and the 100 Interview Tips eBook ($39.99) live in the shop.
Latest Episodes
Browse all 127 episodes →- Oct 17, 2026 Strattera (Atomoxetine) vs Wellbutrin (Bupropion): Non-Stimulant Uses | PMHNP Boards
- Oct 13, 2026 Saphris (Asenapine): Bipolar Mania & Schizophrenia Prescribing | PMHNP Boards
- Oct 11, 2026 Wellbutrin (Bupropion) vs Trintellix (Vortioxetine) After SSRI Failure | PMHNP Boards
- Oct 6, 2026 Vraylar (Cariprazine) vs Abilify (Aripiprazole): D2, D3 Differences | PMHNP Boards
- Sep 29, 2026 Panic Disorder vs PTSD: Differential Diagnosis Case Study | PMHNP Boards
- Sep 22, 2026 Schizoid vs Schizotypal Personality Disorder: Clinical Clues | PMHNP Boards
Pearls in Writing
Deep-dive comparisons from the show, in article formVraylar vs Abilify: What’s the Actual Difference?
Same dimmer-switch engine, different aim. Why Vraylar’s D3 grip matters for negative symptoms, the weeks-long half-life nobody warns you about, and the Abilify impulse-control conversation.
Read the article →Prozac vs Zoloft: The Real Differences Between Two First-Line SSRIs
Efficacy is a tie — the obstacles decide it. The half-life chasm, CYP2D6, cardiac safety data, and how to plan the exit on day one.
Read the article →Lamictal vs Seroquel for Bipolar Depression
The sprinter and the marathoner. The FDA-approval trap every board exam sets, the rash rule, and the estrogen interaction students miss most.
Read the article →Go Beyond the Episode
Get the free 50 Pearls study guide
Join Pearls and Prep on Patreon free and get 50 Pearls from Pearls & Prep — 50 high-yield clinical pearls condensed for quick review.
The full clinical library is the paid heart of Pearls and Prep: every study guide, psychopharm deep dive, and practice-question set NP Z publishes, organized into collections by drug and diagnosis so you can pull exactly the pearl you need before a shift, an exam, or a hard patient. New material lands there first — the podcast is the trailer; the library is the film.
Free Member
The 50 Pearls study guide, plus new-episode extras and community posts.
Mafia Pearl Top tier
$100/month. Live clinical simulations with NP Z — two small-group Zoom sessions a month, never more than 8 members, open office hours, and the full clinical library unlocked. Practice on cases before your first real patient.
Boss Pearl Most popular
The full clinical library — and the 100 Psychiatric Interview Tips eBook, free with this tier.
In the Shop
100 Psychiatric Interview Tips For Your 1st Eval eBook — $39.99 (free for Boss Pearl members).
Free from the Library
Start here — a few favorites from Patreon, on the house50 Pearls from Pearls & Prep
Our free study guide: 50 high-yield clinical pearls from the show, condensed into quick-review lessons you can work through on a lunch break. Join Patreon free and it's yours.
Get the free guide →Free clinical pearls every week
A fresh pearl in your feed every week — a prescribing nuance, a differential that trips people up, a board-style trap to watch for. Follow along free and keep your edge between episodes.
Follow free on Patreon →Sample the Boss Pearl library
Curious what members get? Browse the public previews from the Boss Pearl clinical library — study guides, psychopharm deep dives, and practice questions — and see if it's for you.
Take a look inside →